Testing
Translocations of chromosome 8 are common aberrations in the B-cell non-Hodgkin lymphoma group. The presence of the typical t(8;14) or the rare variants t(8;22) and t(2;8) has been confirmed in…
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BL-CAM, integral membrane glycoprotein, Early B-cell, Hairy Cell leukemia [I CD22]
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BL-CAM, Integral membrane glycoprotein, Early B-Cell, Hairy Cell Leukemia
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Pan B cell, follicular dendritic cells, technical only
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Cyclin-dependent kinase-4, technical only
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The Luminex xTAG® Cystic Fibrosis (CFTR) 39 kit v2 (IVD) allows for the detection and simultaneous identification of a panel of 39 mutations and 4 variants in the cystic fibrosis…
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M CF NGS Seq
CF diagnosis and carrier status Cystic Fibrosis MiSeqDx Clinical Sequence Assay
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I CD25 TC
Stains the alpha subunit of interleukin-2 receptor on the membrane of activated T cells CD25, technical only
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I CD25
Stains the alpha subunit of interleukin-2 receptor on the membrane of activated T cells CD25
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CALR somatic mutations are seen in a subset of patients with MPNs who lack JAK2 and MPL mutations. CALR mutations appear restricted to patients with ET and PMF and are…
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Detection of an abnormal chromosome clone is generally evidence of a clonal neoplastic process; rarely it may be associated with an unrelated congenital non-neoplastic abnormality. Certain abnormal chromosomes may also…
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Combined Immunophenotyping, myeloid / lymphoid markers and Morphology review
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M CEBPA*
Mutations in CEBPA are found in 15-18% of cases of cytogenetically normal AML and are associated with a favorable prognosis. Germline mutations in CEBPA are a cause of nonsyndromic, familial… CEBPA Mutation Analysis
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Cri-du-chat syndrome is a rare genetic condition caused by the deletion of genetic material on the small arm of chromosome 5. Cri-du-chat syndrome occurs in an estimated 1 in 20,000…
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In hematological malignant diseases, recognized recurring chromosomal abnormalities often correlate with particular subtypes of leukemia that have characteristic morphological and clinical features, such as response to therapy. The study of…
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Bone marrow is the tissue of choice for cytogenetic study of most hematologic conditions because it more accurately reflects what occurs in vivo than other sample types. In hematological malignant…
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F CBFB
Structural abnormalities of chromosome 16 involving the CBFB locus have been identified in a specific group of patients with acute myelomonocytic leukemia (AML) type M4 with marked eosinophilia. Inversion 16,… CBFB t(16;16), inv(16)
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Cytogenetic analysis of peripheral blood lymphocytes is performed to detect numerical or structural chromosome abnormalities. There are many indications for performing chromosome studies. These include multiple congenital abnormalities, mental retardation
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Cystic Fribrosis(Amniotic fluid) 32 Mutation Analysis Prenatal Panel
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Leukemias are a diverse group of diseases often characterized by multiple genetic aberrations distributed across the genome. In some cases, the same genetic aberrations are shared by different types of…
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F CMYC
Translocations of chromosome 8 are common aberrations in the B-cell non-Hodgkin lymphoma group. The presence of the typical t(8;14) or the rare variants t(8;22) and t(2;8) has been confirmed in… C MYC 8q24 Rearrangement
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Cell Cycle Analysis; DNA Ploidy and S Phase by Flow cytometry
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Intended for use as a screening test for evidence of Chlamydia trachomatis infection.
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