Testing
The APTIMA Trichomonas vaginalis Assay is an in vitro qualitative nucleic acid amplification test cleared by the FDA for the detection of ribosomal RNA (rRNA) from Trichomonas vaginalis to aid…
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F T21
An extra copy of chromosome 21 is the cause of Down syndrome. An increase risk is seen with the increase in maternal age. Trisomy 21*
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F T12
Trisomy 12 is among the more common recurring chromosomal defects in chronic lymphocytic leukemia (CLL). It has been reported in 15–30% of cases and is correlated with atypical morphology. FISH… Trisomy 12
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F T5T9T15
Aneuploidy is a frequent finding in plasma cell myeloma. Approximately 60-70% of myeloma cases have been reported to have hyperdiploid clones. About 10-20% have been reported to have pseudodiploid clones,… Trisomy 5, 9, 15
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F T8
Trisomy 8 is relatively specific for myeloid disorders and is rarely observed in lymphoid disease. It is found in 10-15% of patients with acute myeloid leukemia (AML), 15-20% of patients… Trisomy 8
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F P53
The p53 tumor suppressor gene is one of the most frequently mutated genes in human cancer with mutations and deletions identified in a wide range of solid tumors and hematological… TP53 17p13 deletion
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F TEL AML1
TEL/AML1 (also known as ETV6/RUNX1) translocation is the most frequent genetic abnormality in childhood B-acute lymphoblastic leukemia (ALL) found in 20-30% of cases. The t(12;21) involves the TEL gene on… TEL(ETV6)/AML1(RUNX1) t(12;21)*
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Molecular characterization of T-cell receptor gene rearrangements and immunoglobulin heavy and light chain gene rearrangement detection is accomplished with reliable and robust tests to identify clonal T-cell and B-cell populations…
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