Test Name
Cell Cycle analysis; DNA Ploidy and S Phase
Test Code
PLOIDY
Synonyms
Cell Cycle Analysis; DNA Ploidy and S Phase
Associations
Breast cancer, Non-small cell lung carcinoma, Bladder cancer
Reflex Testing
None
CPT Codes
88182
Turnaround Time
10
Specimen Stability
Whole blood or bone marrow stable at 18-25°C for up to 48 hours Fresh tissue or body fluid stable at 2-8°C up to 72 hours Frozen tissue stable indefinitely at -20°C Formalin fixed paraffin embedded tissue stable at room temperature indefinitely
Storage & Handling
Ship with ice pack. Protect from extreme temperature. Separate ice pack from specimen.
Causes for Rejections
Insufficient volume; Fresh samples not sent within 24 hours
Description
Cell Cycle Analysis; DNA Ploidy and S Phase by Flow cytometry
References
- Da Costa Silva Neto, Jacinto et al. (2008). DNA content analysis of breast lobular invasive carcinoma. Internet Journal of Pathology. Volume 7 Number 2.
- Yildirim-Assaf, Selma et al. (2007). The prognostic significance of determining DNA content in breast cancer by DNA image cytometry: the role of high grade aneuploidy in node negative breast cancer. J Clin Path. 60:649-655.
- Isobe, Hiroshi et al. (2006). Prognostic and therapeutic significance of the flow cytometric nuclear DNA content in non-small cell lung cancer. Cancer. Volume 65, Issue 6; 1391-1395.
- Bol, M G W et al. (2003). Proliferation markers and DNA content analysis in urinary bladder TaT1 urothelial cell carcinomas: identification of subgroups with low and high stage progression risks. J Clin Path. 56(6):447-52.
