Test Name
Human Papillomavirus, High Risk Only
Test Code
HPV HR
Associations
Human papillomavirus (HPV) cotesting in conjunction with a PAP smear every 5 years is the preferred method for cervical cancer screening of women age 30-64 by The American Cancer Society (ACS), the American Society for Colposcopy and Cervical Patholog
CPT Codes
87624
Turnaround Time
1-3 days
Specimen Requirements
1.0 mL ThinPrep® PAP solution 1.0 mL SurePath™ Test Pack solution
Specimen Stability
ThinPrep/SurePath - 30 days from collection at 18-25°C. Specimens are kept for 21 days after receipt.
Storage & Handling
Ship ambient
Causes for Rejections
Insufficient specimen
Description
Used to screen women with ASC-US cervical cytology results to determine the need for referral to colposcopy. To be used adjunctively with cervical cytology to screen women 30 years of age and older to determine the presence or absence of high risk HPV ty
References
- American Society for Colposcopy and Cervical Pathology
- Castle PE et al (2009). Five-year experience of human papillomavirus DNA and papanicolaou test cotesting. Obstet Gynecol. 113:595-600.
- Wright TC Jr et al. (2007). 2006 consensus guidelines for the management of women with abnormal cervical cancer screening tests. Am J Obstet Gynecol. 197:346-355.
- Mayrand MH et al. (2007). Human Papillomavirus DNA versus papanicolaou screening tests for cervical cancer. NEMJ. 357:1579-88.
- Munoz N et al. (2003). Epidemiologic classification of human papillomavirus types associated with cervical cancer. NEMJ. 348:518.
- Solomon D et al. (2001). Comparison of three management strategies for patients with atypical squamous cells of undetermined significance: baseline results from a randomized trial. J Natl Cancer Inst. 93:293–9.
