Test Name
Factor V (Leiden) G1691A/R506Q Mutation
Test Code
FVLEI*
Synonyms
G1691A , R506Q mutations
Associations
Hypercoagulability, Deep vein thrombosis
CPT Codes
81241
Turnaround Time
2-3 days
Specimen Requirements
5.0 mL (min. 3.0 mL) whole blood EDTA, ACD accepted
Specimen Stability
Stable for 24 hours at 18-25°C Stable 4 days at 2-8°C
Storage & Handling
Ship specimen ambient If shipment delayed, store at 2–8°C and ship with cool/refrigerated pack. (Do not allow the sample to be in direct contact with the cool pack.)
Causes for Rejections
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
References
- Kujovich JL. (2009). Factor V leiden thrombophilia. http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=gene∂=factor-v-leiden.
- Spector EB et al. (2005). Technical standards and guidelines: Venous thromboembolism (Factor v leiden and prothrombin 20210G>A testing): A disease-specific supplement to the standards and guidelines for clinical genetics laboratories. Genet Med. 7:444-453.
- Nagy PL et al. (2004). Molecular diagnosis of hypercoagulable states. Lab Med. 4:214-222.
