Test Name
Trisomy 3
Test Code
F T3
Synonyms
+3, CEP3
Associations
Myeloma, Marginal zone B-cell lymphoma, Polyclonal B-cell lymphocytosis
CPT Codes
88367x1
Turnaround Time
3-5 days
Specimen Requirements
2.0 mL (min. 1.0 mL) peripheral blood in sodium heparin preferred, EDTA accepted 1.0 mL (min. 0.5 mL) bone marrow in sodium heparin preferred, EDTA accepted 5 mm^3 fresh tissue in MPLN RPMI media 3.0 mL (min. 2.0 mL) FNA in MPLN RPMI media 10% neutral buffered formalin fixed paraffin embedded tissue
Specimen Stability
Peripheral blood and bone marrow stable at 18-25°C for 72 hours Fresh tissue or FNA stable at 2-8°C for 72 hours
Storage & Handling
Whole blood and bone marrow, ship ambient Fresh tissue, FNA or paraffin embedded tissue, ship in a Styrofoam container with an cool/refrigerated pack (Do not allow cool/refrigerated pack to directly contact sample)
Causes for Rejections
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells; Improper fixative
Description
By FISH
References
- Wong K. et al. (2002). Cancer Genetics and Cytogenetics. Volume 136, Issue 1. 82-85.
