Test Name
ALL Pediatric Profile
Test Code
F PALL
Synonyms
BCR/ABL 9q34 t(9;22), MLL 11q23, TEL/AML1 t(12;21), trisomy 4, trisomy 10, trisomy 17
Associations
Acute lymphoblastic leukemia (ALL)
CPT Codes
88367, 88373 x10
Turnaround Time
3-5 days
Specimen Requirements
5mL peripheral blood in sodium heparin 3mL bone marrow in sodium heparin Fixed cytogenetically prepared cells in sterile centrifuge tube with pellet visible in 3:1, Methanol:Acetic Acid
Specimen Stability
Peripheral blood and bone marrow stable at 18-25°C for 72 hours
Storage & Handling
Whole blood and bone marrow, ship ambient
Causes for Rejections
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells
Description
9q34 t(9:22), 11q23, t(12;21),+4, +10, +17; by FISH
References
- Karen Seiter. (2009). Acute Lymphoblastic Leukemia, Medscape
- Grant C, Cools J, Michaux L et al. (2006). Cytogenetic and molecular genetics of T-cell acute lymphoblastic leukemia from thymocyte to lymphoblast. Leukemia. 20:1496-1510.
