Test Name
Aneuploidy +13, +18, +21, X, Y*
Test Code
F ANEU
Synonyms
Aneuploidy +13, +18, +21, X, Y, prenatal
Associations
Down syndrom, Edwards syndrome, Patau syndrome, klinefelter syndrome, Turner Syndrome
CPT Codes
88271 x2, 88273, 88274, 88291
Turnaround Time
1
Specimen Requirements
5mL of whole amniotic fluid
Specimen Stability
Amniotic fluid = 4°C to 25°C, specimens are stable up to 48 hours
Storage & Handling
4°C to 25°C during transit, but specimens may be transported on refrigerated gel packs. Do not allow the gel pack to come in contact with the specimen. Do not freeze. Extreme temperatures should be avoided.
Causes for Rejections
Specimen exposed to extreme temperature; Insufficient number of cells
Description
Trisomy 13, trisomy 18 and trisomy 21, and numerical errors of the sex chromosomes (X and Y) constitute the most common chromosome abnormalities observed at prenatal diagnosis. DNA probes specific for chromosomes 13, 18, 21, X and Y permit enumeration of
