Test Name
Chromosome Analysis Amniotic Fluid
Test Code
CYTO AF *
Synonyms
Chromosome analysis, cytogenetic analysis, karyotyping, prenatal diagnosis
Associations
Serum Alpha Fetoprotein (AFP) can be ordered as an add on with CYTO-AF.
Reflex Testing
Reflex to Acetycholinesterase (AChE) testing to rule out a neural tube defect (NTD) when Alpha Fetoprotein (AFP) levels are significantly elevated
CPT Codes
88269,88235,88291
Turnaround Time
7-10 days
Specimen Requirements
20-30 mL amniotic fluid in 2-3 sterile tubes, analysis can be attempted on smaller volumes
Specimen Stability
18-25°C for 48 hours
Storage & Handling
Ship ambient overnight Call before sending specimen on Friday; Ship Saturday for Monday delivery Protect sample from extreme temperature
Causes for Rejections
Specimen exposed to extreme temperature; Insufficient number of cells; Specimen exposed to fixative; Specimen obtained in syringe or tube toxic to cells
Description
Amniotic Fluid
References
- Gerson et al. (1999). Principles of Clinical Cytogenetics. Humana Press: Totowa, New Jersey.
