Test Name
Lung Cancer NGS
Test Code
M LUNG NGS
Synonyms
EGFR, KRAS, BRAF, NRAS,
Associations
NSCLC adenocarcinoma; EGFR, KRAS, BRAF NRAS gene hotspot mutations
Reflex Testing
FISH for ALK translocation (F ALK) can be performed as a reflex or in conjunction with this assay.
CPT Codes
81210, 81235, 81275, 81311
Turnaround Time
10 days
Specimen Requirements
Formalin Fixed Paraffin Embedded tissue block 3 slides (3-5 uM) per marker on adhesion glass NOTE: Include a surgical pathology report with the sample
Specimen Stability
Indefinite at ambient temperature (18-25°C)
Storage & Handling
Ship ambient. Protect from extreme temperature with an ice pack. Separate ice pack from specimen
Causes for Rejections
Insufficient DNA content ; Inadequate fixation; Improper labeling
Description
This sequencing panel is useful in determining eligibility for tyrosine kinase inhibitor (TKI) therapy in patients with non-small cell lung cancer (NSCLC). The EGFR mutation is present in 10-15% of lung adenocarcinomas, and predicts response to drugs such
