Test Name
Chromosome Analysis Lymphoma (Lymph Node)
Test Code
CYTO LN
Synonyms
Chromosome analysis, cytogenetic analysis, karyotyping
Associations
Lymphoma
CPT Codes
By report 88237, 88264, 88280xn, 88291
Turnaround Time
7
Specimen Requirements
10 mm lymph node sample in at least 4 mL tissue culture transport media (RPMI) using 10 mL sterile transport tube Fixed cytogenetically prepared cells in sterile centrifuge tube with 3:1, Methanol:Acetic Acid. Pellet must be visible for the volume part and the medium part 3:1, Methanol:Acetic Acid.
Specimen Stability
4°C to 25°C, specimens are stable up to 72 hours Fixed cell pellets are stable for years when stored at -28°C to -15°C
Storage & Handling
4°C to 25°C during transit, but specimens may be transported on refrigerated gel packs. Do not allow the gel pack to come in contact with the specimen. Do not freeze. Extreme temperatures should be avoided.
Causes for Rejections
Specimen exposed to extreme temperature; Insufficient number of cells; Specimen exposed to formalin or other fixative
Description
Detection of an abnormal chromosome clone is generally evidence of a clonal neoplastic process; rarely it may be associated with an unrelated congenital non-neoplastic abnormality. Certain abnormal chromosomes may also be associated with a morphological c
References
- Dunn, B. (2005). The Cytogenetic Symposia. 2nd edition, 14-1:15-1.
