Test Name
Adult ALL FISH Panel
Test Code
F AALL
Synonyms
BCR/ABL t(9;22),TEL/AML1 t(12;21), MLL(KMTA) 11q23
Associations
Acute lymphoblastic leukemia (ALL)
CPT Codes
88374 x3
Turnaround Time
3-5 days
Specimen Requirements
5mL peripheral blood in sodium heparin 3mL bone marrow in sodium heparin Fixed cytogenetically prepared cells in sterile centrifuge tube with pellet visible in 3:1, Methanol:Acetic Acid
Specimen Stability
Peripheral blood and bone marrow stable at 18-25°C for 72 hours
Storage & Handling
Whole blood and bone marrow, ship ambient
Causes for Rejections
Clotted specimen; Specimen exposed to extreme temperature; Anticoagulant toxic to cells; Insufficient number of cells;
Description
9q34 t(9:22), 11q23, t(12;21);by FISH
References
- Graux C, Cools J, Michaux L, et al. (2006). Cytogenetics and molecular genetics of T-cell acute lymphoblastic leukemia: From thymocyte to lymphoblast. Leukemia 20:1496-1510.
- Karen Seiter. (2009). Acute Lymphoblastic Leukemia, Medscape.
